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Researcher profile


Rosa del Carmen Milán Segovia

Personal Data:
Academic Degree:  PhD Degree
SNI Level: I
Institutional Data:
Affiliation: Faculty of Chemistry

Office Address: Manuel Nava 6 CP. 78210 San Luis Potosí
Phone Number: (+52) 4448262300
Ext.: 6438
  1. PhD Degree in PhD. in Biological Sciences
    Universidad Autónoma Metropolitana Xochimilco
  2. Master's Degree in Master in Biopharmceutics
    Universidad Nacional Autónoma De México
  3. Bachelor's Degree in Chemical Pharmaceutical Biologist
    Universidad Autónoma de San Luis Potosí

I’m a Chemical Pharmaceutical Biologist (UASLP), Master in Biopharmaceutics (UNAM) and PhD. in Biological Sciences (UAM). I work as a Research Professor at the UASLP Faculty of Chemical Sciences. I teach Biopharmaceutics & Pharmacokinetics, and Community & Hospital Pharmacy in the Chemical Pharmaceutical Biologist bachelor’s degree program and Liquid Chromatography, Pharmacoepidemiology and Bioavailability & Bioequivalence Studies in the postgraduate program. My line of research focuses on Biopharmaceutical and Pharmacokinetic Studies for the Rational Drug Use, in which we are investigating aspects that affect bioavailability of drugs and identifying pharmacogenetic factors that influence the disposition of drugs in the body. We are conducting clinical drug monitoring studies, from the implementation of analytical techniques by HPLC-UV and UPLC-MS/MS to quantify drugs in biological fluids and determine their pharmacokinetics profile, as well as the application of molecular techniques by PCR to study the pharmacogenetics of: isoniazid, pyrazinamide and ethambutol, and the polymorphisms of enzymes NAT2, MDR1, CYP2E1 and GSTM1 in patients with tuberculosis; levetiracetam in patients with epilepsy; methotrexate and genetic polymorphisms of SLC19A1, ABCB1, FPGS and GGH in patients with rheumatoid arthritis; 6-mercaptopurine and TPMT polymorphisms in children with acute lymphoblastic leukemia; among others. We are performing studies to individualize dosage regimens, as well as of Clinical Pharmacy and the implementation of Pharmaceutical Services to contribute to the rational and safe use of drugs.

Personal Researchs Interest
  1. Biopharmaceutics and Pharmacokinetics studies for the rational use of drugs.
Research Interests of Research Group
  1. Red Potosina Interinstitucional de Farmacogenética y Monitorización de Fármacos
    08/05/2015 - 15/07/2016
    Fondos Mixtos Gobiernos del Estado de SLP
  2. Influencia Farmacogenética y Farmacocinética en los niveles plasmáticos de fármacos contra la tuberculosis.
    28/04/2015 - 17/12/2015
    Fondo de Apoyo a la Investigación. UASLP
  3. IDENTIFICACIÓN DE POLIMORFISMOS DE NAT2 COMO MARCADORES GENÉTICOS Y SU ASOCIACIÓN CON LA FARMACOCINÉTICA DE ISONIACIDA Y SU METABOLITO. HACIA UNA ESTRATEGIA PARA LA INDIVIDUALIZACIÓN DE LA TERAPIA ANTIFÍMICA EN PACIENTES CON TUBERCULOSIS.
    21/03/2012 - 23/03/2015
    Fondo Sectorial de Investigación en Salud y Seguridad Social (SSA, IMSS, ISSSTE, CONACYT)
  4. Estudio de genotipificación de enzimas NAT1 y NAT2 en sujetos sanos
    28/04/2014 - 17/12/2014
    Fondo de Apoyo a la Investigación. UASLP
  5. Evaluación farmacocinética y estudio de polimorfismo genético de fármacos empleados en el tratamiento de la Tuberculosis.
    15/10/2013 - 29/09/2014
    Fortalecimiento de Cuerpos Académicos. PROMEP
  6. Diagnóstico situacional de la preparacion de mezclas intravenosas en las áreas de neonatología y pediatría.
    29/04/2013 - 27/06/2014
    Hospital del Niño y la Mujer