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gci@uaslp.mx
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Researcher profile


María Guadalupe Martel Gallegos

Personal Data:
Academic Degree:  PhD Degree
SNI Level: I
Institutional Data:
Affiliation: Multidisciplinary Academic Media Campus

Office Address: Carr. San Ciro Km 4 CP. 76915 Rioverde SLP
Phone Number: (+52) 4442307537
Ext.: 4559
Email: guadalupe.martel@uaslp.mx
  1. PhD Degree
    Universidad Autónoma de San Luis Potosí
  2. Master's Degree
    Universidad Autónoma de San Luis Potosí
  3. Bachelor's Degree
    Universidad Autónoma de San Luis Potosí

I am a Research Professor attached to the Nursing Degree. I have training in molecular biology techniques such as interference RNA, DNA and RNA extraction, RT-PCR and Western blot, as well as the analysis of intracellular reactive oxygen and calcium species by spectrofluorometry, phagocytosis of human neutrophils and the P2X7 receptor in the generation of reactive oxygen species in mouse macrophages. Work on determining the signaling pathways that underlie activation of the P2X7 receptor for the generation of reactive species. I have worked on the implementation of cultures of neurons of the dorsal ganglion root and cortical neurons, primary culture of oligodendrocytes (OLG) and the technique of calcium measurement by fluorescence in a single cell for the pharmacological characterization of purinergic receptors and their role in myelination in co-cultures neurons-OLG. I am currently investigating the effects of arsenic on purinergic receptors in an in vitro model for the study of the mechanisms of neurodegeneration in Alzheimer's disease and what is the role of these receptors in the development of neurodegenerative diseases such as Alzheimer's disease and Diabetic encephalopathy?

Personal Researchs Interest
  1. Role of purinergic receptors in the development of neurodegenerative diseases
  2. Role of oxidative stress in neurons exposed to high glucose concentrations as a molecular mechanism of neurodegeneration in diabetes mellitus
  1. Evaluación de la expresión y función de los receptores P2X7 y P2Y2 en la neurodegeración asociada a la Enfermedad de Alzheimer e inducida por arsénico
    26/07/2018 - 31/07/2019
    PRODEP NPTC