I obtained my
Ph.D. in neuroscience at Medicine School, of University Complutense of Madrid (UCM). During my PhD, I studied the
preventing effects of melatonin on metabolic disorders and neuronal pathways,
related to the satiety center in obese male rats induced by a high-fat-diet.
Postdoc researcher, I worked at the Molecular Biology Investigation Laboratory
at Odontology School (UCM), participating in a multicenter clinical trial
project in the analysis of peri-implantosseous defects, evaluating bone
metabolism including inflammation cytokines, cell transcription factors and
cell markers of bone resorption/regeneration and its association with obesity.
principal research includes, neuroendocrine control of food intake and energy
balance, high fat diet, gut-brain axis, circadian rhythms, melatonin, cytokine
expression, gene expression, biomarkers of bone metabolism and toxicology of
metals. Developing as a principal Lines of research, i) the evaluation of the
gene expression at central level related to appetite and satiety under
different treatments and its association response with peripheral level, ii) Inflammatory
assess metabolic comorbidities associated with obesity and its possible
prevention and / or regulation and iii) Assess the degree of metalloproteinases
in obesity and its effects.
In our group we molecular biology techniques, DNA/RNA purification, Quantitative Real Time -
Polymerase Chain Reaction (QRT-PCR) and agarosa gel electrophoresis), protein
techniques (protein purification/Western Blot), flow cytometer (using microspheres/Ag-Ac
complex, lasers and digital signal processing), High Performance Liquid
Chromatography (HPLC), ICPMs and also other conventional measurement techniques
as EIA (Enzyme Immunoassay)/ELISA (Enzyme-Linked
Immuno Sorbent Assay).